The Shape of the Urine Stream — From Biophysics to Diagnostics

نویسندگان

  • Andrew P. S. Wheeler
  • Samir Morad
  • Noor Buchholz
  • Martin M. Knight
چکیده

We develop a new computational model of capillary-waves in free-jet flows, and apply this to the problem of urological diagnosis in this first ever study of the biophysics behind the characteristic shape of the urine stream as it exits the urethral meatus. The computational fluid dynamics model is used to determine the shape of a liquid jet issuing from a non-axisymmetric orifice as it deforms under the action of surface tension. The computational results are verified with experimental modelling of the urine stream. We find that the shape of the stream can be used as an indicator of both the flow rate and orifice geometry. We performed volunteer trials which showed these fundamental correlations are also observed in vivo for male healthy volunteers and patients undergoing treatment for low flow rate. For healthy volunteers, self estimation of the flow shape provided an accurate estimation of peak flow rate (± 2%). However for the patients, the relationship between shape and flow rate suggested poor meatal opening during voiding. The results show that self measurement of the shape of the urine stream can be a useful diagnostic tool for medical practitioners since it provides a non-invasive method of measuring urine flow rate and urethral dilation.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ecomorphology of Kura Berbel (Barbus cyri, De Filippi, 1865) in Sefidrud River Basine

This study was conducted to investigate the relationship between body shape and environmental factors related to a rivarian ecosystem in Kura barbel (Barbus cyri) of the Sefidrud River basin. For this purpose, a number of 285 specimens were sampled from three rivers with different habitat properties including the Taleghan, Totkabon and Kloraz Rivers. The relationship between body shape (extract...

متن کامل

A Semi-empirical Model to Predict the Attached Axisymmetric Shock Shape

In this work, a simple semi-empirical model is proposed, based on Response Surface Model, RSM, to determine the shape of an attached oblique shock wave emanating from a pointed axisymmetric nose at zero angle of attack. Extensive supersonic visualization images have been compiled from various nose shapes at different Mach numbers, along with some others performed by the author for the present p...

متن کامل

DEVELOPMENT OF A METHOD FOR THE DETERMINATION OF 4-HYDROXY-3-METHOXYMANDELIC ACID (VANILLYLMANDELIC ACID) IN URINE BY PAPER CHROMATOGRAPHY

We have developed a simple and precise paper chromatographic method for the determination of 4-hydroxy-3-methoxymandelic acid (VMA) in urine. Concentrations of VMA in patients with neuroblastoma were increased in comparison to controls. The linearity was excellent in the concentration range tested. The within-assay coefficient of variation for control and patient urine was less than 2.2%. ...

متن کامل

Electrochemical miRNA Biosensors: The Benefits of Nanotechnology

The importance of nanotechnology in medical technologies, especially biomedical diagnostics, is indubitable. By taking advantages of nanomaterials, many medical diagnostics methods have been developed so far, including electrochemical nanobiosensors. They have been used for quantification of different clinical biomarkers for detecting, screening, or follow up a disease. microRNAs (miRNAs) are o...

متن کامل

Natural convection from horizontal noncircular annulus partially filled with porous sleeve

In this paper natural convection heat transfer within a two-dimensional, horizontal, concentric cam shape cylinders that is partially filled with a fluid saturated porous medium has been investigated. both cylinder are kept at constant and uniform temperatures with the outer cylinder being subjected relatively lower than the inner one. In addition the forchheimer and brinkman effect are taken i...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2012